Fitzgerald Factor

《英文msh詞典》Fitzgerald Factor
[入口詞] Fitzgerald Factor
[主題詞] Kininogen,High-Molecular-Weight
[英文釋義] A plasma protein,molecular weight of 110 kD,that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction,XIIa,in turn activates prekallikrein to KALLIKREINS. (From Stedman,26th ed)